Here you will find product flyers and information on our products in the field of immunohistology, which you can download as PDF files.
Tenascin C is an extracellular matrix glyco-protein associated with cell motility, proliferation and differentiation. It is widely expressed during embryogenesis but exhibits a very restricted pattern in adults. It is expressed in the lamina propria and in the basement membrane towards the mucosal surface of normal colon mucosa.
Oligodendrocyte Lineage Transcription Factor 2, a basic helix–loop–helix transcription factor, plays a key role in oligodendrocyte and motor neuron differentiation.
The diagnosis of metastatic carcinoma from uncertain primaries or poorly differentiated high-grade neoplasms involving the prostate and adjacent organs can be challenging, especially in the setting of limited cancer foci on a needle biopsy. In practice, the histologic distinction between high-grade prostate cancer and infiltrating high-grade urothelial cancer has significant implications because both tumor entities require different treatments (i.e. hormone therapy for prostate cancer and chemotherapy for urothelial cancer).
Colorectal cancer (CRC) is the third most common cancer diagnosed globally, making up 10 % of all cases. Immunohistochemistry is a widely used tool for diagnosis of CRC especially in untypical cases or in cases where the primary tumor is not known (CUP, Cancer of Unknown Primary).
Thyroid Transcription factor 1 (TTF-1) is a member of the NKX2 family of transcription factors. In pathology diagnostics antibodies to TTF-1 are widely used to identify lung and thyroid origin, not least because TTF-1 retains its sensitivity in metastatic and poorly differentiated tumors.
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